Jack leaves Jill out of sorts (3)
I believe the answer is:
ill
'out of sorts' is the definition.
(thesaurus)
'jack leaves jill' is the wordplay.
'jack' becomes 'j' (playing card abbreviation).
'leaves' indicates named letters should be taken away.
'jill' with 'j' taken out is 'ILL'.
(Other definitions for ill that I've seen before include "Evil or sick" , "weak" , "Badly - in need of medical care" , "In bad health" , "Not in the pink" .)