Keep in favour of temperature (4)
I believe the answer is:
fort
'keep' is the definition.
(I've seen this in other clues)
'in favour of temperature' is the wordplay.
'in favour of' becomes 'for' (I've seen this before).
'temperature' becomes 't' (abbreviation).
'for'+'t'='FORT'
(Other definitions for fort that I've seen before include "& 22 US Army post" , "Defensive building" , "Citadel" , "& 4 Down Army post in USA" , "US gold reserves are at - Knox" .)