Large insect runs inside on the ground (6)
I believe the answer is:
hornet
'large insect' is the definition.
'runs inside on the ground' is the wordplay.
'runs' becomes 'r' (cricket abbreviation**).
'inside' is an insertion indicator.
'ground' is an anagram indicator (grind the letters ).
'on'+'the'='onthe'
'onthe' anagrammed gives 'honet'.
'r' placed within 'honet' is 'HORNET'.
(Other definitions for hornet that I've seen before include "Large social wasp with fierce sting" , "Large wasp with vicious sting" , "Throne (anag.)" , "Vespa" , "A large wasp with severe sting (6)" .)