Left home carried by nun (8)
I believe the answer is:
sinister
'left' is the definition.
(thesaurus)
'home carried by nun' is the wordplay.
'home' becomes 'in' ('he's home' can mean 'he's in').
'carried by' means one lot of letters goes inside another.
'nun' becomes 'sister' (Sister is an example).
'in' put inside 'sister' is 'SINISTER'.
(Other definitions for sinister that I've seen before include "can be injurious" , "Disquieting" , "Suggestive of evil/harm" , "Resist in way that is creepy" , "What is left on bearings" .)