Looked across the road, annoyed (8)
I believe the answer is:
pestered
'annoyed' is the definition.
('pestered' can be a synonym of 'annoyed')
'looked across the road' is the wordplay.
'looked' becomes 'peered' (peering is a kind of looking**).
'across' indicates putting letters inside.
'the road' becomes 'st'.
'peered' enclosing 'st' is 'PESTERED'.
(Other definitions for pestered that I've seen before include "Annoyed continually" , "Annoyed with frequent questions or requests" , "Constantly bothered by deer pets" , "Harassed, annoyed" , "Badgered with repeated requests" .)