Lots of work around hospital department (6)
I believe the answer is:
plenty
'lots of' is the definition.
(I've seen this before)
'work around hospital department' is the wordplay.
'work' becomes 'ply' (I've seen this before**).
'around' indicates putting letters inside.
'hospital department' becomes 'ent'.
'ply' enclosing 'ent' is 'PLENTY'.
(Other definitions for plenty that I've seen before include "Copiousness" , "A full supply - lots" , "Masses" , "Many" , "A great deal" .)