MacFarlane of "Family Guy" (4)
I believe the answer is:
seth
'macfarlane of family guy' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for seth that I've seen before include "Adam and Eve's third son" , "In disguise, the brother of Cain and Abel" , "said to sound archaic" , "Younger brother to Cain and Abel" , "god of Egypt" .)