Man born of a mother? No! (4)
I believe the answer is:
Here is my best explanation:
'man' is the definition.
(Adam is an example)
'a mother? no' is the wordplay.
'mother? no' becomes 'dam' (female parent of an animal. I am not sure about the 'no' bit.**).
'born of' acts as a link.
(Other definitions for adam that I've seen before include "neoclassical style", "who transformed the Palladian style?", "first in the race?", "Biblical progenitor of human race", "one might confuse with total stranger", "First man of Genesis", "Robert ..., ... Clayton", "First fruit-eater", "Eves husband" and "One of our common ancestors?".)