Mean at home to nurse (6)
I believe the answer is:
intend
'mean' is the definition.
(to intend to something is to mean it)
'at home to nurse' is the wordplay.
'at' means one lot of letters go next to another.
'home' becomes 'in' (to be in is to be (at) home).
'to nurse' becomes 'tend' (tend can mean to nurse or look after).
'in'+'tend' is 'INTEND'.
(Other definitions for intend that I've seen before include "Mean - purpose" , "Plan, propose" , "Mean; aim" , "Have as purpose or in mind" , "Have as purpose or plan" .)