Nothing gets ahead of the greatest, latest thing (5)
I believe the answer is:
omega
'latest thing' is the definition.
(last letter of the Greek alphabet)
'nothing gets ahead of the greatest' is the wordplay.
'nothing' becomes 'o' (looks like zero - 0).
'gets ahead of' says to put letters next to each other.
'the greatest' becomes 'mega'.
'o'+'mega'='OMEGA'
(Other definitions for omega that I've seen before include "Final Greek letter" , "Art of story-telling by body movement" , "Traditional story" , "Final outcome" , "16 letter" .)