Off to visit Virginia holiday home? (5)
I believe the answer is:
villa
'holiday home?' is the definition.
(villa can mean a rented holiday home)
'off to visit virginia' is the wordplay.
'off' becomes 'ill'.
'to visit' is an insertion indicator (inserted letters visit others).
'virginia' becomes 'va' (US state abbreviation).
'ill' going inside 'va' is 'VILLA'.
(Other definitions for villa that I've seen before include "Rented holiday home" , "Type of house" , "SECOND PART OF 8" , "Roman domicile" , "A place in the country" .)