Open University head under pressure (7)
I believe the answer is:
Here is my best explanation:
'open' is the definition.
I don't know anything about this answer so I cannot tell whether this works.
'university head under pressure' is the subsidiary indication.
'university' becomes 'u'.
'head' becomes 'front' (I've seen this in other clues**).
'under' is a charade indicator (letters next to each other).
'pressure' becomes 'p' (abbreviation).
'front' put after 'p' is 'pfront'.
(Other definitions for upfront that I've seen before include "Honest - paid in advance", "Bold, frank (colloq.)", "Candid", "In advance", "Informally, straightforward or frank", "Straightforward or prominent", "Open, honest", "Open - paid at start of transaction", "Open - frank - paid out beforehand (of money)" and "(Of payment) in advance".)