Painter calling home, possibly about start of employment (12)
I believe the answer is:
michelangelo
'painter' is the definition.
(Michelangelo is an example)
'calling home possibly about start of employment' is the wordplay.
'possibly' is an anagram indicator.
'about' is an insertion indicator.
'start of' indicates taking the first letters.
The first letter of 'employment' is 'e'.
'calling'+'home'='callinghome'
'callinghome' with letters rearranged gives 'michlangelo'.
'michlangelo' placed around 'e' is 'MICHELANGELO'.
(Other definitions for michelangelo that I've seen before include "Famous sculptor" , "genius" , "Sistine ceiling painter" , "Italian painter and sculptor" , "Italian sculptor (David)" .)