Passion displayed by north eastern girl (5)
I believe the answer is:
Here is my best explanation:
'girl' is the definition.
(I've seen this before)
'passion displayed by north eastern' is the subsidiary indication.
'passion' becomes 'ire'.
'displayed by' is a charade indicator (letters next to each other).
'north' becomes 'n' ('N' can be a synonym of 'north').
'eastern' becomes 'e'.
(Other definitions for irene that I've seen before include "Peaceful girl", "One can find a girl in Ree", "Girl's name; Soames Forsyte's first wife", "The girl of peace", "representative", "Greek godess of peace", "She", "Girl of peace", "Representative of peace" and "Greek goddess of peace (English name)".)