Point to the sign –LADIES” (5)
I believe the answer is:
women
'ladies' is the definition.
(I know this)
'point to the sign' is the wordplay.
'point' becomes 'w' (West).
'to the sign' becomes 'omen' (omen is a kind of sign).
'w'+'omen'='WOMEN'
(Other definitions for women that I've seen before include "half of our race" , "Adult human females" , "Ladies" .)