Poles apart in pipes too? Wrong! (8)
I believe the answer is:
Here is my best explanation:
'poles apart' is the definition.
'pipes too? wrong' is the wordplay.
'wrong' indicates an anagram.
'pipestoo' anagrammed gives 'opposite'.
'in' is the link.
(Other definitions for opposite that I've seen before include "Facing on the other side", "Face to face or directly contrary", "Oppose it, being faced against", "antipodean", "Reverse or antithesis", "On the other side", "Rival", "Adverse", "across the road?" and "Facing - reverse".)