Practise economy, extremely likely without effect (9)
I believe the answer is:
uselessly
'without effect' is the definition.
I can't judge whether this defines the answer.
'practise economy extremely likely' is the wordplay.
'practise economy' becomes 'useless' (I can't explain this - if you can you should believe this answer much more).
'extremely' suggests removing the centre (only the extremes of the word are used).
'likely' with its middle removed is 'ly'.
'useless'+'ly'='USELESSLY'
Can you help me to learn more?
(Another definition for uselessly that I've seen is " in vain".)