Produced a second-class road out East (4)
I believe the answer is:
bred
'produced' is the definition.
(breeding is a kind of producing)
'a second-class road out east' is the wordplay.
'a second class' becomes 'b'.
'road' becomes 'rd' (abbreviation for road).
'out' indicates putting letters inside.
'east' becomes 'e' (abbreviation).
'rd' going around 'e' is 'red'.
'b'+'red'='BRED'
(Other definitions for bred that I've seen before include "Developed (animal variety)" , "Engendered" , "Gave rise to" , "Propagated, raised" , "Brought up (to behave in particular way)" .)