Scotsman given drugs becomes gentler (5)
I believe the answer is:
tames
'becomes gentler' is the definition.
I can't judge whether this definition defines the answer.
'scotsman given drugs' is the wordplay.
'scotsman' becomes 'tam' (I can't explain this - if you can you should believe this answer much more).
'given' means one lot of letters go next to another.
'drugs' becomes 'es' (ecstasy tablets).
'tam'+'es'='TAMES'
Can you help me to learn more?
(Other definitions for tames that I've seen before include "Domesticates an animal" , "Subdues" .)