Section of orchestra should refuse (5)
I believe the answer is:
trash
'refuse' is the definition.
(thesaurus)
'section of orchestra should' is the wordplay.
'section of' says the answer is hidden in the clue.
'TRASH' is hidden within 'orchestra should'.
(Other definitions for trash that I've seen before include "Refuse; wreck" , "Condemn" , "Drivel" , "Garbage or nonsense" , "Worthless people; destroy (US slang)" .)