Set up Mev's goal for City (5)
I believe the answer is:
miami
'city' is the definition.
(Miami is an example)
'set up mev's goal' is the wordplay.
'set up' says the letters should be written backwards (in a down clue, letters go up).
'mev' becomes 'im' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'goal' becomes 'aim' (aim is a kind of goal).
'im'+'aim'='imaim'
'imaim' reversed gives 'MIAMI'.
'for' acts as a link.
Can you help me to learn more?
(Other definitions for miami that I've seen before include "Port in Florida" , "Popular city in SE Florida" , "Resort city in SE Florida" , "place associated with vice?" , "Sunshine city in SE Florida" .)