Sibling nurses at home on the left (8)
I believe the answer is:
sinister
'the left' is the definition.
(thesaurus)
'sibling nurses at home' is the wordplay.
'sibling' becomes 'sister' (I've seen this before).
'nurses' is an insertion indicator.
'at home' becomes 'in' ('in' can be similar in meaning to 'at home').
'sister' enclosing 'in' is 'SINISTER'.
'on' is the link.
(Other definitions for sinister that I've seen before include "Spooky" , "Menacing" , "What is left on bearings" , "Threatening; evil-looking" , "Resist in way that is creepy" .)