Skin irritation (4)
I believe the answer is:
itch
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">skin irritation</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for itch that I've seen before include "A strong restless desire" , "Irritate" , "burn" , "A nagging desire" , "cause irritation" .)