Spiked a Republican, snared by drug (7)
I believe the answer is:
speared
'spiked' is the definition.
(spearing is a kind of spiking)
'a republican snared by drug' is the wordplay.
'republican' becomes 'R' (abbreviation in US politics).
'snared by' means one lot of letters goes inside another.
'drug' becomes 'speed' (speed is a kind of drug).
'a'+'r'='ar'
'ar' put inside 'speed' is 'SPEARED'.
(Another definition for speared that I've seen is " hit by javelin maybe!".)
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