Crossword Genius

Spots in part of East London, as locals may pronounce it? (4)


I believe the answer is:


'spots' is the definition.
(skin condition causing spots)

I don't understand the rest of the clue.

(Other definitions for acne that I've seen before include "Inflammation of glands in skin" , "Skin problem, mainly of teenagers" , "Pimply skin condition of adolescence" , "Pimply ailment of adolescnce" , "sort of disease" .)

I've seen this clue in The Times.
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