Take on inspiring role in puzzle (6)
I believe the answer is:
Here is my best explanation:
'puzzle' is the definition.
(I've seen this before)
'take on inspiring role' is the wordplay.
'take' becomes 'be' (being is a kind of taking).
'on' is an insertion indicator (as in clothing \'on\' a person).
'inspiring role' becomes 'emus' (I am not sure about this - if you are sure you should believe this answer much more).
'be' enclosing 'emus' is 'BEMUSE'.
'in' is the link.
(Other definitions for bemuse that I've seen before include "Stupefy, puzzle", "Floor", "Confound", "Confuse, bewilder", "Nonplus", "Perplex", "Puzzle and confuse", "Bewilder or baffle", "Muddle or stupefy" and "Cause puzzlement".)