Take over from with ease (7)
I believe the answer is:
Here is my best explanation:
This clue is a double definition.
'take over from' is the first definition.
('relieve' can be a synonym of 'take over from')
'ease' is the second definition.
('relieve' can be a synonym of 'ease')
'with' is the link.
(Other definitions for relieve that I've seen before include "Ease pain or burden", "Make less tedious, bring aid to (besieged place)", "Set free", "comfort", "Ease or take over from", "Assuage - take over duty from", "free of duty", "Take over (from) - ease worries (of)", "Alleviate 9pain)" and "Comfort".)