Take over from with ease (7)
I believe the answer is:
relieve
I believe this clue is a double definition.
'take over from' is the first definition.
(synonyms)
'ease' is the second definition.
(synonyms)
'with' acts as a link.
(Other definitions for relieve that I've seen before include "Alleviate (eg, pain)" , "Assuage - take over duty from" , "Make less tedious, bring aid to (besieged place)" , "Palliate" , "Take over (from) - ease worries (of)" .)