Takes on again that woman's upset and anger with son (7)
I believe the answer is:
rehires
'takes on again that woman's upset and anger with son' is the definition.
'rehires' can be an answer for 'takes on again' (I've seen this in another clue). I am unsure of the remainder of the definition.
'takes on' is the wordplay.
I cannot quite understand how this works, but
'takes' could be 'hires' ('hire' can be a synonym of 'take') and 'hires' is present in the answer.
'on' could be 're' ('on' can be mean 'with reference to') and 're' is found within the answer.
No letters remain.
This explanation may well be incorrect...
Can you help me to learn more?
(Another definition for rehires that I've seen is " Perhaps releases".)