Tender rose arrangement (4)
I believe the answer is:
sore
'tender' is the definition.
(synonyms)
'rose arrangement' is the wordplay.
'arrangement' indicates anagramming the letters.
'rose' with letters rearranged gives 'SORE'.
(Other definitions for sore that I've seen before include "Hurt" , "source of distress" , "Painfully sensitive" , "Hurting, painful" , "Painful spot" .)