Tiny amphibian belonging to me picked up (6)
I believe the answer is:
minute
'tiny' is the definition.
(minute can mean small)
'amphibian belonging to me picked up' is the wordplay.
I cannot quite see how this works, but
'me' could be 'mi' (both are spellings of the musical note) and 'mi' is found in the answer.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for minute that I've seen before include "Sixty seconds" , "60 seconds; tiny" , "barely noticeable?" , "Immeasurably small" , "Small, tiny" .)