Tory Party first to mandate Anti-Labour measure (6)
I believe the answer is:
condom
'anti-labour measure' is the definition.
I can't tell whether this defines the answer.
'tory party first to mandate' is the wordplay.
'tory' becomes 'con' (abbreviation for conservative).
'party' becomes 'do' (do can informally mean a party).
'first to' says to take the initial letters.
The initial letter of 'mandate' is 'm'.
'con'+'do'+'m'='CONDOM'
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