Urge simple changes around university (7)
I believe the answer is:
impulse
'urge' is the definition.
('impulse' can be a synonym of 'urge')
'simple changes around university' is the wordplay.
'changes' is an anagram indicator.
'around' indicates putting letters inside.
'university' becomes 'u'.
'simple' is an anagram of 'implse'.
'implse' enclosing 'u' is 'IMPULSE'.
(Other definitions for impulse that I've seen before include "A sudden inclination to act (7)" , "Sudden urge to act" , "Whim; thrust" , "Miles up (anag)" , "Impel us with sudden urge" .)