Wholly new great hotel (10)
I believe the answer is:
altogether
'wholly' is the definition.
(I know that wholly can be written as altogether)
'new great hotel' is the wordplay.
'new' is an anagram indicator.
'great'+'hotel'='greathotel'
'greathotel' anagrammed gives 'ALTOGETHER'.
(Other definitions for altogether that I've seen before include "totally" , "Quite" , "Completely, on the whole" , "Wholly" , "nude in this" .)