Crossword Genius

William —, Best Actor in a Leading Role Oscar winner for Kiss of the Spider Woman (4)

Ross

I believe the answer is:

hurt

(Other definitions for hurt that I've seen before include "John -, actor (The Elephant Man); harm" , "Cause pain to" , "Injure - injury" , "Ache" , "Injure, harm" .)

I've seen this clue in The Mirror.
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