Blasphemous university academic article on ecstasy (7)
I believe the answer is:
profane
'blasphemous' is the definition.
(I know that blasphemous can be written as profane)
'university academic article on ecstasy' is the wordplay.
'university academic' becomes 'prof' (I've seen this before).
'article' becomes 'an' (indefinite article).
'on' means one lot of letters go next to another (in a down clue, letters appear on others).
'ecstasy' becomes 'E' (informal term for the drug).
'prof'+'an'+'e'='PROFANE'
(Other definitions for profane that I've seen before include "Irreverent - pagan" , "vulgar" , "Secular, not religious" , "Treat with irreverence" , "Secular; obscene" .)