Huge waste ending in ruin of philosopher (9)
I believe the answer is:
epicurean
'philosopher' is the definition.
(thesaurus)
'huge waste ending in ruin' is the wordplay.
'huge' becomes 'epic' (I've seen this in another clue).
'waste' becomes 'urea' (compound in urine).
'ending in' says to take the final letters.
The last letter of 'ruin' is 'n'.
'epic'+'urea'+'n'='EPICUREAN'
'of' is the link.
(Other definitions for epicurean that I've seen before include "Foodie's" , "immoderate character" , "pleasure-seeker" , "expert at the table" , "follower of luxury" .)