Prickle removed from wreath or nosegay (5)
I believe the answer is:
thorn
'prickle' is the definition.
(I know that prickle can be written as thorn)
'removed from wreath or nosegay' is the wordplay.
'removed from' indicates a hidden word.
'THORN' can be found hidden inside 'wreath or nosegay'.
(Other definitions for thorn that I've seen before include "pain in one's side" , "Pointed growth" , "prickly type" , "sharp object" , "Spike on a rose bush" .)