Ready to keep on suffering pollution? (8)
I believe the answer is:
poisoned
'suffering pollution?' is the definition.
(pollution introduces poisonous material to a place)
'ready to keep on' is the wordplay.
'ready' becomes 'poised' (as in being poised to do something).
'to keep' indicates putting letters inside.
'poised' enclosing 'on' is 'POISONED'.
(Other definitions for poisoned that I've seen before include "Administered a toxin" , "Administered venom" .)