Rum lab rebuilt round ruined manor (8)
I believe the answer is:
abnormal
'rum' is the definition.
(I've seen this before)
'lab rebuilt round ruined manor' is the wordplay.
'rebuilt' is an anagram indicator.
'round' means one lot of letters goes inside another.
'ruined' is an anagram indicator.
'lab' anagrammed gives 'abl'.
'manor' is an anagram of 'norma'.
'abl' going around 'norma' is 'ABNORMAL'.
(Other definitions for abnormal that I've seen before include "Irregular" , "Deviant, different from the usual" , "Rum" , "'Aberrant, atypical (8)'" , "Odd" .)