Weary; tried a new way (5)
I believe the answer is:
tired
'weary' is the definition.
(similar in meaning)
'tried a new way' is the wordplay.
'a new way' indicates an anagram.
'tried' with letters rearranged gives 'TIRED'.
(Other definitions for tired that I've seen before include "Sleepy" , "Worn-out" , "Drowsy" , "In need of rest" , "Weary or fed up" .)