A question of personal welfare (3,3,3)
I believe the answer is:
how are you
'a question of personal welfare' is the definition.
I can't tell whether this defines the answer.
'a question of' is the wordplay.
I cannot quite understand how this works, but
'a' is within the answer.
'question' could be 'how' (I've seen this in other clues) and 'how' is present in the answer.
'of' could be 'o' and 'o' is located in the answer.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for how are you that I've seen before include "Solicitous inquiry" , "Solicitous greeting" , "Conventional greeting, enquiry about well-being" .)