Abandoned European souvenir in outskirts of Detroit (8)
I believe the answer is:
derelict
'abandoned' is the definition.
(synonyms)
'european souvenir in outskirts of detroit' is the wordplay.
'european' becomes 'E' (abbreviation e.g. EU).
'souvenir' becomes 'relic' (synonyms).
'in' means one lot of letters goes inside another.
'outskirts of' means to remove the middle letters.
'detroit' with its middle taken out is 'dt'.
'e'+'relic'='erelic'
'erelic' placed within 'dt' is 'DERELICT'.
(Other definitions for derelict that I've seen before include "Abandoned and falling into ruin" , "Ramshackle" , "Deserted - vagrant" , "Social outcast" , "Deserted and neglected" .)