At university, drunk and tense (7)
I believe the answer is:
uptight
'tense' is the definition.
(similar in meaning)
'at university drunk' is the wordplay.
'at university' becomes 'up' (slang term meaning at university).
'drunk' becomes 'tight' (slang term).
'up'+'tight'='UPTIGHT'
'and' is the link.
(Other definitions for uptight that I've seen before include "Tip thug, being nervous and tense" , "Informally, nervously tense and anxious" , "Nervous, tense, anxious" , "Unable to express one's feelings" , "nervy state" .)