Baffles husband with tissue (5)
I believe the answer is:
flesh
'tissue' is the definition.
(I know that flesh is a type of tissue)
'baffles husband with' is the wordplay.
'with' indicates a hidden word.
'FLESH' is hidden in the letters of 'baffles husband'.
(Other definitions for flesh that I've seen before include "Edible part of fruit" , "Edible fruit pulp" , "Substance of animal body on shelf" , "Excess weight" , "Soft tissue of animals" .)