Big, bold characters made to swallow ecstasy and some coke (8)
I believe the answer is:
headline
'big bold characters made to swallow ecstasy and some coke' is the definition.
I can't judge whether this defines the answer.
'made to swallow ecstasy and some coke' is the wordplay.
'made' becomes 'had' ('have' can be a synonym of 'make').
'to swallow' means one lot of letters goes inside another.
'ecstasy' becomes 'E' (informal term for the drug).
'and' means one lot of letters go next to another.
'some coke' becomes 'line' (a line of cocaine).
'had' enclosing 'e' is 'head'.
'head'+'line'='HEADLINE'
Can you help me to learn more?
(Other definitions for headline that I've seen before include "Writing above newspaper article" , "Caption on a newspaper article" , "Prominent text" , "Newspaper title" , "Article title" .)