Check a little puncture in wheel (5)
I believe the answer is:
repel
'check' is the definition.
(thesaurus)
'a little puncture in wheel' is the wordplay.
'a little' indicates taking the first letters.
'in' means one lot of letters goes inside another.
'wheel' becomes 'reel' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
The first letter of 'puncture' is 'p'.
'p' going into 'reel' is 'REPEL'.
Can you help me to learn more?
(Other definitions for repel that I've seen before include "Drive back or away" , "Drive or force back" , "Drive away or disgust" , "Sicken" , "Fill with distaste" .)