Contemptuous daughter is fluid with an arrangement (10)
I believe the answer is:
disdainful
'contemptuous' is the definition.
(I know that contemptuous can be written as disdainful)
'daughter is fluid with an arrangement' is the wordplay.
'daughter' becomes 'd' (genealogical abbreviation).
'with' means one lot of letters go next to another.
'arrangement' indicates anagramming the letters.
'fluid' put after 'an' is 'anfluid'.
'anfluid' is an anagram of 'dainful'.
'd'+'is'+'dainful'='DISDAINFUL'
(Other definitions for disdainful that I've seen before include "Contemptuous" , "Showing contempt" .)