Cruel chums stripped man naked in pub (7)
I believe the answer is:
inhuman
'cruel' is the definition.
(inhuman can mean cruel or inhumane)
'chums stripped man naked in pub' is the wordplay.
'stripped' says to take the centre.
'naked' says to take the centre.
'in' indicates putting letters inside.
'pub' becomes 'inn' (an inn is a type of pub).
The central letters of 'chums' are 'hum'.
The middle letter of 'man' is 'a'.
'hum'+'a'='huma'
'huma' put within 'inn' is 'INHUMAN'.
(Other definitions for inhuman that I've seen before include "Without compunction" , "barbarous and brutal" , "Callously cruel" , "Nasty" , "Cruel, bestial" .)