Cure ado made in a South American republic (7)
I believe the answer is:
ecuador
'a south american republic' is the definition.
(I've seen this in another clue)
'cure ado made' is the wordplay.
'made' indicates an anagram.
'cure'+'ado'='cureado'
'cureado' is an anagram of 'ECUADOR'.
'in' acts as a link.
(Other definitions for ecuador that I've seen before include "S. American nation" , "South American republic" , "Where panama hats are made" , "The state capital is Quito" , "The Galapagos Islands are part of its territory" .)