Curse foul rupturing organ (4,3)
I believe the answer is:
evil eye
'curse' is the definition.
(I've seen this before)
'foul rupturing organ' is the wordplay.
I cannot quite understand how this works, but
'foul' could be 'vile' (synonyms) and 'vile' is found in the answer.
'organ' could be 'eye' (eye is a kind of organ) and 'eye' is found within the answer.
No letters remain.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for evil eye that I've seen before include "Look supposed to have the power to harm" , "Gaze believed harmful" , "Nasty look" , "Supposedly harmful stare" , "Stare with the power to harm?" .)